Adhesion–Growth Factor Interactions during Differentiation: An Integrated Biological Response
نویسندگان
چکیده
منابع مشابه
An Integrated Network Approach to Identifying Biological Pathways and Environmental Exposure Interactions in Complex Diseases
Complex diseases are the result of intricate interactions between genetic, epigenetic and environmental factors. In previous studies, we used epidemiological and genetic data linking environmental exposure or genetic variants to phenotypic disease to construct Human Phenotype Networks and separately analyze the effects of both environment and genetic factors on disease interactions. To better c...
متن کاملMedlineDB : An integrated biological text mining framework
MedlineDB is a schema and framework for integrating Medline abstracts with common biological organism databases for improved text analysis. The framework utilizes and extends existing, well-known biological database schemata and tools for loading data from various sources and provides utilities to use those sources in several common datamining tasks. MedlineDB brings together the best of featur...
متن کاملTranscriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y.
To understand the molecular mechanism by which interleukin-6 (IL-6) regulates myeloid differentiation primary response (MyD) genes at the onset of M1 myeloid differentiation, we used JunB as a representative MyD gene to isolate and characterize IL-6 responsive elements. An IL-6 responsive element was localized between -65 and -52 of the JunB promoter (-65/-52 IL-6RE). By using antibody and olig...
متن کاملBiological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis
Hypoxia Inducible Factor (HIF) is the main transcription factor that mediates cell response to hypoxia. Howeverthe complex factor cascades induced by HIF during regenerative angiogenesis are currently incompletely mapped and the biological outcome mediated by chronic HIF induction during vessel regeneration are not well known. Here, we investigated the biological impact of HIF induction on vasc...
متن کاملIdentification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation.
Serum-response factor (SRF) is an obligatory transcription factor, required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Protein A-TEV-tagged chromatin immunoprecipitation technology was used to collect direct SRF-bound gene targets from pluripotent P19 cells, induced by Me2SO treatment into an enriched cardiac cell population. From 242 sequenced ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Biology
سال: 1996
ISSN: 0012-1606
DOI: 10.1006/dbio.1996.0319